Published
2021-10-06
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Articles
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COVID-19: Vaccines on Their Marks
Ekta Jagtiani
Department of Polymers and Surface Coatings Technology, Institute of Chemical Technology, Mumbai 400019
Darsh Vithlani
Department of Speciality Chemicals Technology, Institute of Chemical Technology, Mumbai 400019
DOI: https://doi.org/10.36664/bt/2021/v68i1/162888
Keywords: SARS-CoV-2, Immunity, Vaccines, Safety Profile, Clinical Trials, Efficacy, Oxford, Pfizer, Moderna.
Abstract
Vaccine-derived immunity is being optimistically heralded as the exit strategy to the pandemic, thereby enabling everyone to return to the much-awaited normal patterns of working, schooling, and socialising. The SARS-COV-2 (COVID-19) respiratory virus was first identified in December 2019 in Wuhan, China. Owing to the rampant spread of the virus there was an exigency that called for the development of a vaccine. In this review, we discuss what is currently known about the mechanism of action, efficacy, safety profile, clinical trials, and distribution of three of the most promising vaccine candidates; mRNA-1273 (Moderna), BNT162b2 (Pfizer/BioNtech), ChAdOx1 nCoV-19 (AstraZeneca/Oxford). In the race to come up with a safe and effective vaccine against the novel coronavirus, there are a myriad of factors that play a critical role throughout the development, clinical trials, manufacturing, distribution phases. An in-depth insight is given into the expected scope and the speculated limitations of the aforementioned vaccines.Downloads
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