Rapid Detection of Tuberculosis without Pain and Blood: Biosensors Offer New Alternatives

Varun Patel

Shobhit Gogia

Keywords: Biosensors, Tuberculosis, Piezoelectric, Immunosensing.


Abstract

Biosensors are chemical sensors that take advantage of the high selectivity, and sensitivity of a biologically active material. The objective of the research described here is to use biosensor technology to develop a rapid method for the diagnosis of tuberculosis and other infections caused by mycobacteria. The work encompassed here describes the construction of antibody-based piezoelectric crystals capable of detecting mycobacterial antigens in diluted cultures of attenuated M. tuberculosis in an immunologically specific manner. The antigens were detected 4n either liQuid or vapor phase

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