GENES : A Novel Treatment for SCLC
Palak M. Shah
Pharmaceutical Sciences and Technology Department
Abstract
Small Cell Lung Cancer (SCLC) is a highly aggressive cancer with widespread metastasis at presentation. SCLC patients have a poor prognosis with very high mortality when treated by standard treatment designs of chemotherapy, radiotherapy and occasionally surgery, and novel treatment regimes for this malignancy are therefore in great need. As cancers are basically abnormalities in cell growth mediated by altered genetic material, gene therapy constitutes a promising alternative fourth treatment modality for SCLC either in combination with conventional treatment modalities or alone. Targeted gene therapy in the form of transcriptionally targeted gene therapy, tumor suppressor genes and suicide genes is being investigated for SCLC.Downloads
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