Pharmacochemical Nano-Switches

Anuradha D. Sakharkar

B.Pharmacy

Keywords: Nano-Switches, Hydrazones, pH, Nanoimpellers, Nanovalves.


Abstract

Hydrazones undergo a configurational and/or conformational changes on sequential addition of acid and base. This gives an on/off switching function to the molecule Also dualcontrolled nanoparticles exhibiting AND logic can act as a switch. Spectroscopy like 1H NMR is used to study the working and action of these molecules. Such chemical molecular switches help in attaining even more sophisticated levels of controlled release and site targeted drug delivery.

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