Medicated Chewing Gums: A Revolution in Self-Medication And Drug Delivery
Samruddhi Sunil Sontakke
Institute of Chemical Technology, Mumbai-400019
DOI: https://doi.org/10.36664/bt/2023/v70i1/173196
Keywords: Medicated Chewing Gums, Buccal Administration
Abstract
Medicated chewing gums (MCGs) are characterized as ‘solid single-dose preparations with a base consisting
mainly of gum that is intended to be chewed but not to be swallowed, providing a slow steady release of the
medicine contained’. The European Pharmacopoeias (Ph. Eur) along with the U.S. Pharmacopoeias (USP)
formally acknowledged medicated chewing gums as an acceptable method for medication administration.
MCGs have become a new and exciting method in the realm of oral drug delivery. The potential benefits of
chewing gums over conventional drug delivery method are examined in this review paper. Notable benefits
include the circumvention of hepatic first-pass effect, patient compliance, local and systemic action, and
various other advantages that make them an exciting alternative in pharmaceutical research. This
comprehensive review paper covers all essential aspects related to medicated chewing gums, including their
composition, advantages, disadvantages, methods of preparation, and future trends. It also underscores the
potential of medicated chewing gums as a useful substitute to buccal medication delivery and emphasizesthe
need for further exploration and research in this field.
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