Published
2022-11-21
Section
Review Article
How to Cite
The Thyroid and Cardiovascular System: A clinical synergy
Aditya Shinde
Department of Pharmaceutical Sciences and Technology; Institute of Chemical Technology, Mumbai -400019.
DOI: https://doi.org/10.36664/bt/2022/v69i1/172489
Keywords: Thyroid Hormone; Cardiovascular disease; Hyperthyroidism; Hypothyroidism; Atrial Fibrillation
Abstract
The thyroid hormone exerts many direct and indirect effects on the heart and the cardiovascular system. The myocardial and vascular endothelial cells of the cardiovascular system contain the necessary receptors for the molecules of the Thyroid Hormone to bind to and are affected by the changes in the levels of the circulating hormones in the blood plasma. The significance of the hormonal action in maintaining the homeostatic balance of the cardiovascular system is based upon decades of clinical trials and experimental analysis. Even minor fluctuations in the concentrations of these hormones, such as in the case of sub-clinical hypothyroidism, can cause serious harm to the heart and vascular system. This review article will establish the precise course of action of the thyroid hormones on the heart and the cardiovascular system and discuss its potential therapeutic applications for improving patients’ health conditions and resultantly cardiovascular disorders.
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