Published
2022-11-21
Section
Review Article
How to Cite
Applications of Algal Based Therapeutics in Human Health
Pritish Roy
Department of Oils, Oleochemicals and Surfactants Technology; Institute of Chemical Technology; Mumbai 400019.
Sharvari M. Patil
Department of Oils, Oleochemicals and Surfactants Technology; Institute of Chemical Technology; Mumbai 400019.
Deepro Bandyopadhyay
Department of Pharmaceutical Sciences and Technology; Institute of Chemical Technology; Mumbai 400019
DOI: https://doi.org/10.36664/bt/2022/v69i1/172488
Keywords: algae, bioactive compounds, pharmaceutical applications, sulfated polysaccharides, algal metabolites.
Abstract
Algae are microorganisms abundant in our world’s ecosystems and are present in the form of pond scum, seaweed, phytoplankton, cyanobacteria etc. The algae produce multiple primary and secondary metabolites as a result of their intrinsic biochemical pathways. The metabolites are biologically active molecules such as polysaccharides, proteins, fatty acids, pigments, vitamins, minerals and other further complex molecules. These compounds can be harnessed for pharmaceutical applications due to their inherent properties or derivatives which possess desired properties such as antioxidant, anti-inflammatory, antitumour, anticancer, antiviral and antimicrobial characteristics. They have benefits of being less toxic, biodegradable and vastly available due to the large number and variety of algae present in our world. This review paper discusses the properties of such bioactive molecules as well as their current and potential applications. The application areas discussed are drug delivery systems, cancer, COVID-19, cardiovascular diseases and as an alternative to antibiotics.
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References
J. P. Keshri, R. Mukhopadhyay, , 2012, 31-50
F. Khavari, M. Saidijam, M. Taheri, F. Nouri, Mol Biol Rep., 2021, 48:5,1
M. Bhattacharjee, Asian J Pharm Clin Res., 2016, 9:6, 43
Available at https://www.researchandmarkets.com/report s/5448171
M. S. Aw, S. Simovic, Y. Yu, J. Addai-Mensah, D. Losic, Powder Technol., 2012, 223, 52
J. Sánchez, M.D. Curt, N. Robert, J. Fernández. The Role of Bioenergy in the Bioeconomy. Academic Press, 2019, 25-111,
E. Shannon, N. Abu-Ghannam. Phycologia. 2019, 58:5, 563
A. Celso, S. Joana, P. Susete, G. Helena, A. Maria C., B. Luis M., P. Rui. Front. Pharmacol. 2018, 9:777, 1
I.S.Shchelik, S.Sieber, K.Gademann. Chem. Eur. J. 2020, 26,16644
Ludmylla Cunha; and Ana Grenha. Mar. Drugs. 2016, 14, 42.
Tomoda, K., Asahiyama, M., Ohtsuki, E., Nakajima, T., Terada, H., Kanebako, M., Inagi, T., Makino, K. Colloids Surf., B, 2009, 71, 27.
Leong, K.H., Chung, L.Y., Noordin, M.I., Onuki, Y., Morishita, M.,Takayama, K. Carbohydr. Polym. 2011, 86, 555.
Sezer, A.D., Akbu˘ ga.J. J. Microencapsul. 2006, 23, 513.
Tabata, Y., Ikada, Y. Biomaterials. 1988, 9, 356
Sugita-Konishi, Y.; Yamashita, S.; Amano, F.; Shimizu, M. Biosci. Biotechnol. Biochem. 2003, 67, 1425
Mohamed E. Abd El-Hacka, Sameh Abdelnourb, Mahmoud Alagawanya, Mohamed Abdoc, Moustafa A. Sakrd, Asmaa F. Khafagae, Samir A. Mahgoubf, Shaaban S. Elnesrg, Manar G. Gebrielh. Biomed. Pharmacother. 2019, 111, 42
Yuezhen Ouyang, Yinghui Qiu, Yuning Liu, Ruiyu Zhu, Yihan Chen, Hesham R. El-Seedi, Xinhua Chen, Chao Zhao.Food Res. Int. 2021, 147, 110522.
B. Holst, G. Williamson, Curr. Opin. Biotech. 2008, 19 ,73.
G. Prabakaran, M. Moovendhan, A. Arumugam, A. Matharasi, R. Dineshkumar,P. Sampathkumar. Int. J. Pharm. Biol. Sci. 2018, 8, 562.
P. Palozza, C. Torelli, A. Boninsegna, R. Simone, A. Catalano, M.C. Mele, N. Picci. Cancer Lett. 2009, 283, 108.
E.B. Damonte, M.C. Matulewicz, A.S. Cerezo. Curr. Med. Chem. 2004, 11, 2399.
I.C. Sheih, T.J. Fang, T.K. Wu, P.H. Lin. J. Agric. Food Chem. 2009, 58, 1202.
W.W. Carmichael. J. Appl.Bacteriol. 1992, 72, 445.
A. Tzachor, O. Rozen, S. Khatib, S. Jensen, D. Avni, Mar Biotechnol, 2021, 23, 149
R. Sangtani, A. Ghosh, H.C. Jha, H.S. Parmar, K. Bala, Phytotherapy Res., 2020, 35:5, 1
W.Y. Chia, H. Kok, K.W. Chew, S.S. Low, P.L. Show, Bioengineered, 2021, 12:1, 1226-1237
N. Hans, A. Malik, S. Naik, Bioresour. Technol., 2021, 13, 100623
Tatyana Zaporozhets & Natalia Besednova.Pharmaceutical Biology. 2016, 54,3126.
Nishino T, Nagumo T.. Carbohydr Res.1991, 214, 193.
Durand E, Helley D, Al Haj Zen A, Dujols C, Bruneval P, Colliec-Jouault S, Fischer AM, Lafont A. J Vasc Res. 2008, 45:529–537.
Casu B, Naggi A, Torri G. Matrix Biol. 2010, 29, 442.
Boisson-Vidal C, Zemani F, Caligiuri G, Galy-Fauroux I, Colliec-Jouault S, Helley D, Fischer AM.Cardiovasc Hematol Agent Med Chem. 2007, 5, 67
B.K. Das, J. Pradhan, Indian J. Fish., 2010, 57:2, 61
K. Kolanjinathan, D. Stella, Recent Res. in Sci. and Technol., 2009, 1:1, 20
S. Bhowmick, A. Mazumdar, A. Moulick, V. Adam, Biotechnol. Adv., 2020, 43, 107571
O.N. Ayrapetyan, E.D. Obluchinskaya, E.V. Zhurishkina, Y.A. Skorik, D.V. Lebedev, A.A. Kulminskaya, I.M. Lapina, Biology, 2021, 10:1, 67
